Selective, high affinity, non-competitive α1A adrenoceptor antagonist (Ki = 0.35 nM). Exhibits no significant activity against a range of other GPCRs, including α2A, β1 and β2 adrenoceptors. Antagonizes effects of phenylephrine on isolated rabbit prostate muscle in vitro and on intra-urethral pressure in rats.

五味子素是一种具有抗哮喘、抗癌和抗炎作用的化合物。

TC-O 9311 是一种有效的 GPR139 激动剂。